Champions Manchester City suffered a stunning 1-0 home defeat to Stoke City on Saturday as their cast of attacking talents were blunted in a lifeless display that cost them their first dropped points of the season.
Manchester City have dominated English football in recent years under Pep Guardiola, although they finished second to Liverpool in the Premier League this season, but have yet to add Europe's most coveted prize to their trophy cabinet.
City, storming towards their third league title in four years, scored three late goals to wrap up victory and move onto 65 points with 11 games left to play ahead of Manchester United on 50 points with a game in hand.
Barcelona and Paris St Germain claimed impressive victories at Manchester City and Bayer Leverkusen respectively in the first legs of their Champions League last 16 ties on Tuesday.
Images from the English Premier League matches on Saturday.
Responding to an initiative already run by fans of both clubs, City and United will donate 50,000 pounds each to the Trussell Trust, a support network of more than 1,200 food banks.
IMAGES from the Champions League matches played on Tuesday.
Erling Haaland and Phil Foden scored hat-tricks to fire champions Manchester City to a rampant 6-3 thrashing of local rivals Manchester United in the English Premier League on Sunday.
IMAGES from EPL match played between Manchester City and Chelsea on Sunday
Images from the EPL matches played on Sunday
Former Manchester United forward Wayne Rooney urged Cristiano Ronaldo to remain patient and make the most of the opportunities that come his way as the Portugal international looks to work his way back into the Premier League club's first team.
Manchester City opened up a two-point lead over their neighbours Manchester United at the top of the English Premier League on Saturday thanks to another display of scintillating brilliance in a 7-2 thrashing of Stoke City at the Etihad Stadium.
Images from the Premier League matches played on Saturday.
Manchester United's calamitous week hit rock bottom as Bournemouth famously consigned them to a 2-1 defeat on Sunday and, to rub salt into the wounds, neighbours Manchester City moved back to the top of the English Premier League.
IMAGES from the English Premier League matches played on Wednesday.
Five images from last week's action in Europe for you to savour.
Images from the English Premier League matches played on Saturday.
Manager Arsene Wenger wants Arsenal to reinforce their title credentials by beating Manchester City in the Premier League on Sunday and called on his players to show no fear at the Etihad Stadium.
Manchester United dropped their first points of the season in a 1-1 draw at Stoke City on Saturday but ended the day top of the Premier League while Chelsea striker Fernando Torres scored and was sent off in his side's 4-1 win over Swansea City.
Champions Manchester City have won their last 10 home league matches scoring a total of 36 goals.
Sarri unmoved as Chelsea capitulation harms top-four hopes
Manchester City captain Vincent Kompany is likely to be sidelined for about a month after suffering a recurrence of a calf problem on Tuesday as his side qualified for the Champions League quarter-finals.
A Sergio Aguero hat-trick helped Manchester City get back to winning ways in the Premier League with a 3-1 victory over Newcastle United, as they stayed 12 points ahead of Manchester United who had to dig deep to secure a 1-0 win at Burnley.
Manchester City lost 1-0 to Manchester United on Wednesday but hung on to reach the League Cup final 3-2 on aggregate and will face Aston Villa at Wembley. Nemanja Matic's 35th-minute strike gave United victory at the Etihad Stadium but the midfielder was later sent off and it was not enough to overturn the 3-1 deficit from the semi-final first leg at Old Trafford.
Manchester City rediscovered their swagger to beat Chelsea 2-0 and move into the quarter-finals of the FA Cup on Saturday, Manuel Pellegrini winning the battle of tactical wits against Jose Mourinho.
A round-up of Saturday's action in the Premier League.
Manchester City manager Manuel Pellegrini said a fond Etihad Stadium farewell to the supporters on Sunday but it was hardly the feel good, celebratory goodbye that he or the fans craved.
Leroy Sane struck the winner as Manchester City beat Liverpool 2-1 in a gripping English Premier League clash.
Liverpool should not be considered favourites when they travel to face Manchester City in the Premier League on Sunday, manager Juergen Klopp said on Friday, despite his side's impressive record against teams near the top of the table.
Sergio Aguero scored twice as Manchester City thrashed Manchester United 4-1 in the Premier League at the Etihad stadium on Sunday.
Sergio Aguero scored twice as Manchester City thrashed Manchester United 4-1 in the Premier League at the Etihad stadium on Sunday.
Images from Saturday's action in the English Premier League.
Images from the English Premier League matches played on Sunday.
Haaland now has an astonishing 42 goals for City since joining from Borussia Dortmund last June.
Chelsea's American forward Christian Pulisic scored his first Premier League goals for the club with a hat-trick and Willian added another in an entertaining 4-2 win at Burnley.
Nine people have been charged after Sunday's derby between Manchester City and Manchester United, police said on Monday although they are still trying to identify the person who threw a coin at Rio Ferdinand.
A huge roar erupted in the Etihad Stadium on Sunday as the final Premier League table was displayed on the giant screens with Manchester City on top and Manchester United's name highlighted in seventh place.
Images from the English Premier League matches played on Saturday.
Both their sides are unbeaten and are well-placed in the Premier League table on nine points but Arsenal manager Arsene Wenger was clearly the happier after his side drew 1-1 at the fortress-like home of Roberto Mancini's Manchester City on Sunday.
Whether that unusual arrangement had any influence on untypical performance from City, who lacked zip and inspiration as they struggled to break down the French side, is a matter of pure guesswork and Arteta wasn't in the mood to be drawn on it.